Detalhe da pesquisa
1.
A finely balanced order-disorder equilibrium sculpts the folding-binding landscape of an antibiotic sequestering protein.
Proc Natl Acad Sci U S A
; 121(20): e2318855121, 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38709926
2.
Molecular and thermodynamic determinants of self-assembly and hetero-oligomerization in the enterobacterial thermo-osmo-regulatory protein H-NS.
Nucleic Acids Res
; 52(5): 2157-2173, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38340344
3.
Probing excited state 1Hα chemical shifts in intrinsically disordered proteins with a triple resonance-based CEST experiment: Application to a disorder-to-order switch.
Methods
; 218: 198-209, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607621
4.
Conformational Tuning Shapes the Balance between Functional Promiscuity and Specialization in Paralogous Plasmodium Acyl-CoA Binding Proteins.
Biochemistry
; 62(20): 2982-2996, 2023 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37788430
5.
Weakening of interaction networks with aging in tip-link protein induces hearing loss.
Biochem J
; 478(1): 121-134, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33270084
6.
Phosphorylation of Thr9 Affects the Folding Landscape of the N-Terminal Segment of Human AGT Enhancing Protein Aggregation of Disease-Causing Mutants.
Molecules
; 27(24)2022 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36557898
7.
Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses.
Hum Mol Genet
; 28(1): 1-15, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30215702
8.
Molecular origins of folding rate differences in the thioredoxin family.
Biochem J
; 477(6): 1083-1087, 2020 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32187349
9.
Controlling Structure and Dimensions of a Disordered Protein via Mutations.
Biochemistry
; 59(2): 171-174, 2020 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31557007
10.
Non-specific DNA-driven quinary interactions promote structural transitions in proteins.
Phys Chem Chem Phys
; 22(22): 12671-12677, 2020 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32458879
11.
Protein plasticity driven by disorder and collapse governs the heterogeneous binding of CytR to DNA.
Nucleic Acids Res
; 46(8): 4044-4053, 2018 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29538715
12.
Tunable order-disorder continuum in protein-DNA interactions.
Nucleic Acids Res
; 46(17): 8700-8709, 2018 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30107436
13.
Thermally versus Chemically Denatured Protein States.
Biochemistry
; 58(21): 2519-2523, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31083972
14.
Engineering Order and Cooperativity in a Disordered Protein.
Biochemistry
; 58(19): 2389-2397, 2019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002232
15.
pStab: prediction of stable mutants, unfolding curves, stability maps and protein electrostatic frustration.
Bioinformatics
; 34(5): 875-877, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29092002
16.
A self-consistent structural perturbation approach for determining the magnitude and extent of allosteric coupling in proteins.
Biochem J
; 474(14): 2379-2388, 2017 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28522638
17.
A General Mechanism for the Propagation of Mutational Effects in Proteins.
Biochemistry
; 56(1): 294-305, 2017 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27958720
18.
Prediction of change in protein unfolding rates upon point mutations in two state proteins.
Biochim Biophys Acta
; 1864(9): 1104-1109, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27264959
19.
Graded Structural Polymorphism in a Bacterial Thermosensor Protein.
J Am Chem Soc
; 139(2): 792-802, 2017 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27991780
20.
Toward a quantitative description of microscopic pathway heterogeneity in protein folding.
Phys Chem Chem Phys
; 19(31): 20891-20903, 2017 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28745340